Molecule Details
InChIKeyYLJPQGVBJWZONC-UHFFFAOYSA-N
Compound Name8-[1-[3-(dimethylamino)propyl]pyrazol-4-yl]-9-ethyl-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Canonical SMILESCCc1cc2c(cc1-c1cnn(CCCN(C)C)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.76
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.4 IC50 ChEMBL;BindingDB
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 8.1 IC50 ChEMBL;BindingDB
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 7.8 IC50 ChEMBL;BindingDB
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 7.8 IC50 ChEMBL;BindingDB
Q9HC35 EML4 Homo sapiens Human PF23409 PF23414 PF03451 7.8 IC50 ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.6 IC50 ChEMBL;BindingDB