Molecule Details
InChIKeyYLBRHUHHQIYMSH-UHFFFAOYSA-N
Compound NamePDE5-IN-6c
Canonical SMILESCOc1ccc(CNc2c3c(nc4ccc(C#N)cc24)CCN(C(C)=O)C3)cc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.91
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O76074 PDE5A Homo sapiens Human PF01590 PF00233 10.2 IC50 ChEMBL;BindingDB
O43924 PDE6D Homo sapiens Human PF05351 7.5 IC50 ChEMBL
P16499 PDE6A Homo sapiens Human PF01590 PF00233 7.5 IC50 ChEMBL;BindingDB
P18545 PDE6G Homo sapiens Human PF04868 7.5 IC50 ChEMBL
P35913 PDE6B Homo sapiens Human PF01590 PF00233 7.5 IC50 ChEMBL
P51160 PDE6C Homo sapiens Human PF01590 PF00233 7.5 IC50 ChEMBL;BindingDB
Q13956 PDE6H Homo sapiens Human PF04868 7.5 IC50 ChEMBL