InChIKey	YKPUWZUDDOIDPM-SOFGYWHQSA-N
Compound Name	Capsaicin
Canonical SMILES	COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.77
Source	ChEMBL;BindingDB

DrugBank ID	DB06774
Drug Name	Capsaicin
CAS Number	404-86-4
Groups	approved investigational
ATC Codes	M02AB01 N01BX04
Description	Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived ...

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Categories: Alkaloids Alkenes Amides Analgesics Anesthetics Anesthetics, Local Antipruritics Basic Lotions and Liniments Benzene Derivatives Capsaicin and Similar Agents Cholinesterase Inhibitors Cytochrome P-450 CYP1A2 Inducers Cytochrome P-450 CYP1A2 Inducers (strength unknown) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2E1 Substrates Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Lipids Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates Peripheral Nervous System Agents Phenols Polyunsaturated Alkamides Sensory System Agents Solanaceous Alkaloids TRPV1 Channel Agonists Topical Products for Joint and Muscular Pain

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Cross-references: BindingDB: 20461 ChEBI: 3374 CHEMBL294199 ChemSpider: 1265957 Drugs Product Database (DPD): 3610 C06866 D00250 PDB: 4DY PubChem:1548943 PubChem:347827793 RxCUI: 1992 Wikipedia: Capsaicin ZINC: ZINC000001530575