Molecule Details
| InChIKey | YKFSGPSMOHAYEG-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(Cyclopentylamino)-6-(3,5-difluorophenylamino)-1,3,5-triazine-2-carbonitrile |
| Canonical SMILES | N#Cc1nc(Nc2cc(F)cc(F)c2)nc(NC2CCCC2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.23 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43235 | CTSK | Homo sapiens | Human | PF08246 PF00112 | 7.7 | IC50 | ChEMBL |
| O60911 | CTSV | Homo sapiens | Human | PF08246 PF00112 | 6.7 | IC50 | ChEMBL |
| P07711 | CTSL | Homo sapiens | Human | PF08246 PF00112 | 6.7 | IC50 | ChEMBL |
| P25779 | Trypanosoma cruzi | Pathogen | PF12131 PF08246 PF00112 | 7.8 | IC50 | ChEMBL;BindingDB |