Molecule Details
| InChIKey | YIRUASIRQWZPIZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-acetyl-8-chloro-2-(2,4-dibromophenylamino)-5-methylquinolin-4(1H)-one |
| Canonical SMILES | CC(=O)c1c(Nc2ccc(Br)cc2Br)[nH]c2c(Cl)ccc(C)c2c1=O |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.56 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07384 | CAPN1 | Homo sapiens | Human | PF01067 PF13833 PF00648 | 6.6 | IC50 | ChEMBL;BindingDB |
| P18505 | GABRB1 | Homo sapiens | Human | PF02931 PF02932 | 6.6 | pIC50 | TTD_MultiTarget |
| Q8I6Z5 | PMV | Plasmodium falciparum (isolate 3D7) | Pathogen | PF00026 PF14543 | 6.6 | pIC50 | TTD_MultiTarget |