Molecule Details
| InChIKey | YIMMYYIRSBUOIA-LADGPHEKSA-N |
|---|---|
| Compound Name | (S)-N-(3-(1H-imidazol-5-yl)propyl)-1-((R)-2-amino-3,3-diphenylpropanoyl)pyrrolidine-2-carboxamide |
| Canonical SMILES | N[C@@H](C(=O)N1CCC[C@H]1C(=O)NCCCc1c[nH]cn1)C(c1ccccc1)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.91 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 7.8 | Ki | ChEMBL;BindingDB |
| P07477 | PRSS1 | Homo sapiens | Human | PF00089 | 6.6 | Ki | ChEMBL |
| P07478 | PRSS2 | Homo sapiens | Human | PF00089 | 6.6 | Ki | ChEMBL |
| P35030 | PRSS3 | Homo sapiens | Human | PF00089 | 6.6 | Ki | ChEMBL |