Molecule Details
| InChIKey | YHMLMIWKVKHAPH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(6-(3-chloro-5-fluorobenzyloxy)naphthalen-2-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Canonical SMILES | CC(C)n1nc(-c2ccc3cc(OCc4cc(F)cc(Cl)c4)ccc3c2)c2c(N)ncnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.54 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 7.0 | IC50 | ChEMBL;BindingDB |
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 8.4 | IC50 | BindingDB |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.4 | IC50 | ChEMBL;BindingDB |
| A3FQ16 | Cryptosporidium parvum (strain Iowa II) | Pathogen | PF13499 PF00069 | 6.4 | IC50 | BindingDB |