Molecule Details
| InChIKey | YHEHVRSGKUYDON-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-Chloro-6-(4-hydroxyphenyl)-2-naphthol |
| Canonical SMILES | Oc1ccc(-c2ccc3c(Cl)c(O)ccc3c2)cc1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.21 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB07119 |
|---|---|
| Drug Name | 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50168323 CHEMBL364092 ChemSpider: 4810212 PDB: 4NA PubChem:6102690 PubChem:99443590 ZINC: ZINC000013645009
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P18505 | GABRB1 | Homo sapiens | Human | PF02931 PF02932 | 8.6 | pIC50 | TTD_MultiTarget |
| Q92731 | ESR2 | Homo sapiens | Human | PF12497 PF00104 PF00105 | 8.6 | IC50 | ChEMBL;BindingDB |
| P03372 | ESR1 | Homo sapiens | Human | PF12743 PF00104 PF02159 PF00105 | 7.0 | IC50 | ChEMBL;BindingDB |
| Q96WX4 | erg6 | Pneumocystis carinii (strain B80) | Pathogen | PF08241 PF08498 | 8.6 | pIC50 | TTD_MultiTarget |