Molecule Details
InChIKeyYGKFZWJWKPZPQM-UHFFFAOYSA-N
Compound Name1-(5-Hydroxynaphthalen-1-yl)-3-pyrazin-2-ylurea
Canonical SMILESO=C(Nc1cnccn1)Nc1cccc2c(O)cccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.55
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 8.2 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.9 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.7 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.2 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.0 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.0 Ki ChEMBL