4-[3-[[3-(6-cyano-3-pyridinyl)-1,4-dihydroindeno[2,1-d]pyrazol-7-yl]oxy]propyl]-N-methylpiperazine-1-carboxamide

InChIKey	`YGJKHDBRTOPTNK-UHFFFAOYSA-N`
Compound Name	4-[3-[[3-(6-cyano-3-pyridinyl)-1,4-dihydroindeno[2,1-d]pyrazol-7-yl]oxy]propyl]-N-methylpiperazine-1-carboxamide
Canonical SMILES	`CNC(=O)N1CCN(CCCOc2ccc3c(c2)-c2[nH]nc(-c4ccc(C#N)nc4)c2C3)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	8
Pfam Stratification	Cross-Family
Avg pChEMBL	6.54
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.3	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	7.0	Ki	ChEMBL
Q7KZI7	MARK2	Homo sapiens	Human	PF02149 PF00069 PF00627	6.6	Ki	ChEMBL
P07333	CSF1R	Homo sapiens	Human	PF00047 PF25305 PF07714	6.4	Ki	ChEMBL
P27448	MARK3	Homo sapiens	Human	PF02149 PF00069 PF00627	6.4	Ki	ChEMBL
Q08881	ITK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	6.3	Ki	ChEMBL
O14965	AURKA	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
O96017	CHEK2	Homo sapiens	Human	PF00498 PF00069	6.1	Ki	ChEMBL