Molecule Details
| InChIKey | YGIABALXNBVHBX-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide |
| Canonical SMILES | CCN(CC)c1ccc2c(C)c(-c3ccc(N4C(=O)C=CC4=O)cc3)c(=O)oc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.58 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q09472 | EP300 | Homo sapiens | Human | PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q03330 | GCN5 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Pathogen | PF00583 PF00439 | 6.6 | IC50 | BindingDB |
| Q07794 | RTT109 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Pathogen | PF08214 | 6.6 | IC50 | ChEMBL |