Molecule Details
| InChIKey | YFXZFROOGCONFB-MRXNPFEDSA-N |
|---|---|
| Compound Name | 4-[2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-6-{[(2r)-2-Amino-3-Phenylpropyl]oxy}-1-Ethyl-1h-Imidazo[4,5-C]pyridin-4-Yl]-2-Methylbut-3-Yn-2-Ol |
| Canonical SMILES | CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(OC[C@H](N)Cc3ccccc3)cc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.36 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31749 | AKT1 | Homo sapiens | Human | PF00169 PF00069 PF00433 | 9.5 | IC50 | ChEMBL;BindingDB |
| Q9Y243 | AKT3 | Homo sapiens | Human | PF00169 PF00069 PF00433 | 8.5 | IC50 | ChEMBL;BindingDB |
| P31751 | AKT2 | Homo sapiens | Human | PF00169 PF00069 PF00433 | 8.3 | IC50 | ChEMBL;BindingDB |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 7.1 | IC50 | ChEMBL;BindingDB |