Molecule Details
| InChIKey | YFOWWQUPARMZQZ-HJRUQSCCSA-N |
|---|---|
| Compound Name | ethyl (2Z,5S)-5-(3-acetylphenyl)-2-[(1-benzylindol-3-yl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate |
| Canonical SMILES | CCOC(=O)C1=CN=c2s/c(=C\c3cn(Cc4ccccc4)c4ccccc34)c(=O)n2[C@H]1c1cccc(C(C)=O)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.3 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43521 | BCL2L11 | Homo sapiens | Human | PF08945 PF06773 | 6.5 | Ki | ChEMBL |
| Q07817 | BCL2L1 | Homo sapiens | Human | PF00452 PF02180 | 6.5 | Ki | ChEMBL |
| P10415 | BCL2 | Homo sapiens | Human | PF00452 PF02180 | 6.2 | Ki | ChEMBL |
| P55957 | BID | Homo sapiens | Human | PF06393 | 6.2 | Ki | ChEMBL |
| Q07820 | MCL1 | Homo sapiens | Human | PF00452 | 6.1 | Ki | ChEMBL |