Molecule Details
InChIKeyYFNWWNRZJGMDBR-UHFFFAOYSA-N
Canonical SMILESCn1cc(C2=Nc3cc(NC(=O)C(N)C4CCCCC4)cc4c3C2=CNNC4=O)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)35
Pfam Stratification Cross-Family
Avg pChEMBL7.12
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (35)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 9.7 Kd ChEMBL
Q2M2I8 AAK1 Homo sapiens Human PF00069 8.7 Kd ChEMBL
Q6ZSR9 Homo sapiens Human PF15282 8.7 Kd ChEMBL
Q9NSY1 BMP2K Homo sapiens Human PF15282 PF00069 8.2 Kd ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 8.0 Kd ChEMBL
Q12866 MERTK Homo sapiens Human PF00041 PF00047 PF13927 PF07714 7.8 Kd ChEMBL
Q9NQU5 PAK6 Homo sapiens Human PF00786 PF00069 7.7 Kd ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 7.7 Kd ChEMBL
O14976 GAK Homo sapiens Human PF00069 PF10409 7.6 Kd ChEMBL
Q32MK0 MYLK3 Homo sapiens Human PF00069 7.5 Kd ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 7.5 Kd ChEMBL
Q96L34 MARK4 Homo sapiens Human PF02149 PF00069 PF00627 7.4 Kd ChEMBL
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 7.3 Kd ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.3 Kd ChEMBL
O96013 PAK4 Homo sapiens Human PF00786 PF00069 7.3 Kd ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 7.0 Kd ChEMBL
Q16512 PKN1 Homo sapiens Human PF02185 PF00069 PF00433 6.9 Kd ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.9 Kd ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.9 Kd ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.8 Kd ChEMBL
P37173 TGFBR2 Homo sapiens Human PF08917 PF07714 6.8 Kd ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.7 Kd ChEMBL
P53671 LIMK2 Homo sapiens Human PF00412 PF00595 PF07714 6.7 Kd ChEMBL
Q9UKE5 TNIK Homo sapiens Human PF00780 PF00069 6.6 Kd ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.5 Kd ChEMBL
O95835 LATS1 Homo sapiens Human PF00069 PF00433 PF00627 6.4 Kd ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.4 Kd ChEMBL
Q9Y2K2 SIK3 Homo sapiens Human PF00069 PF23312 6.4 Kd ChEMBL
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Kd ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.3 Kd ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.2 Kd ChEMBL
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 6.2 Kd ChEMBL
O14578 CIT Homo sapiens Human PF00780 PF00169 PF00069 PF00433 6.1 Kd ChEMBL
P54619 PRKAG1 Homo sapiens Human PF00571 6.1 Kd ChEMBL
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.1 Kd ChEMBL