Molecule Details
| InChIKey | YFGBQHOOROIVKG-FKBYEOEOSA-N |
|---|---|
| Compound Name | Metenkefalin |
| Canonical SMILES | CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.53 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12668 |
|---|---|
| Drug Name | Metenkefalin |
| CAS Number | 58569-55-4 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Metenkefalin is an endogenous opioid and beta-endorphin.[A203225] It has been shown to reduce chromosomal abberations in patients with multiple sclerosis.[A203210] Metenkefalin, along with [tridecactide], are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,... |
Categories: Amino Acids, Peptides, and Proteins Enkephalin, Methionine Enkephalins Experimental Unapproved Treatments for COVID-19 Nerve Tissue Proteins Neuropeptides Neurotransmitter Agents Opioid Peptides Peptides Proteins Receptors, Opioid, delta, agonists mu-Opioid Receptor Agonist
Cross-references: BindingDB: 50019056 ChEBI: 189868 CHEMBL13786 ChemSpider: 391597 C11684 PubChem:443363 PubChem:347828872 RxCUI: 1349278 Wikipedia: Met-enkephalin ZINC: ZINC000004102171