Molecule Details
InChIKeyYDWMUCKJUNLURC-UHFFFAOYSA-N
Compound NameThieno[3,2-c]pyridin-4-amine, 3-(2-methyl-1H-indol-5-yl)-7-[3-(methylsulfonyl)phenyl]-
Canonical SMILESCc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)24
Pfam Stratification Cross-Family
Avg pChEMBL7.04
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (24)
Target Gene Organism Category Pfam pChEMBL Type Source
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 8.8 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 8.4 Ki ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 8.3 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 8.2 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.8 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 7.7 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.4 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 7.4 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.2 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 7.1 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.9 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.8 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.5 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.1 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.0 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.0 IC50 ChEMBL
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL