Molecule Details
InChIKeyYCFRZMCRPHNZOC-QAQDUYKDSA-N
Canonical SMILESCOC(=O)N1CCN([C@H]2CC[C@H](Nc3ncnc4ccc(C#N)cc34)CC2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.84
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 7.4 IC50 ChEMBL
P24863 CCNC Homo sapiens Human PF16899 PF00134 7.2 IC50 ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 7.1 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.2 IC50 ChEMBL