Molecule Details
InChIKeyYBYYWUUUGCNAHQ-LLVKDONJSA-N
Compound NameSra-737
Canonical SMILESN#Cc1cnc(Nc2cc(NC[C@H]3CNCCO3)c(C(F)(F)F)cn2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.69
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB16876
Drug NameSRA-737
CAS Number1489389-18-5
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 328993 CHEMBL4169078 ChemSpider: 58145124 ZINC: ZINC000205442186
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
Q8TD08 MAPK15 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
Q15139 PRKD1 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.5 IC50 ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.4 IC50 ChEMBL
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 6.4 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.2 IC50 ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.2 IC50 ChEMBL
O60285 NUAK1 Homo sapiens Human PF00069 6.2 IC50 ChEMBL