(E)-N-(4-(N-(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)sulfamoyl)phenyl)-4-(dimethylamino)but-2-enamide

InChIKey	`YBVSJBLXFZBKSU-IZZDOVSWSA-N`
Compound Name	(E)-N-(4-(N-(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)sulfamoyl)phenyl)-4-(dimethylamino)but-2-enamide
Canonical SMILES	`CN(C)C/C=C/C(=O)Nc1ccc(S(=O)(=O)Nc2cccc(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)c2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.26
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q00535	CDK5	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL
Q15078	CDK5R1	Homo sapiens	Human	PF03261	6.3	IC50	ChEMBL;BindingDB
Q16584	MAP3K11	Homo sapiens	Human	PF07714 PF14604	6.3	IC50	ChEMBL;BindingDB