Molecule Details
InChIKeyYBAWYTYNMZWMMJ-UHFFFAOYSA-N
Compound NameIdalopirdine
Canonical SMILESFc1ccc2c(CCNCc3cccc(OCC(F)(F)C(F)F)c3)c[nH]c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.26
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11957
Drug NameIdalopirdine
CAS Number467459-31-0
Groups investigational
ATC Codes nan
DescriptionIdalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease.

Categories: Amines Antidepressive Agents Benzene Derivatives Benzyl Compounds Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Hydrocarbons, Fluorinated Hydrocarbons, Halogenated Neurotransmitter Agents Serotonin Agents Serotonin Receptor Antagonists
Cross-references: BindingDB: 50019754 CHEMBL3286580 ChemSpider: 19878969 PubChem:21071390 PubChem:347828282 Wikipedia: Idalopirdine ZINC: ZINC000095936819
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P50406 HTR6 Homo sapiens Human PF00001 9.1 Ki ChEMBL;BindingDB
P28335 HTR2C Homo sapiens Human PF00001 6.6 Ki ChEMBL;BindingDB
P28223 HTR2A Homo sapiens Human PF00001 6.1 Ki ChEMBL;BindingDB