Molecule Details
| InChIKey | YAGLZRLKRDTHPW-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[4-(cyclopropylmethoxy)-5-piperazin-1-yl-2-pyridinyl]-1-propan-2-ylimidazo[4,5-h]quinazolin-8-amine |
| Canonical SMILES | CC(C)n1cnc2ccc3cnc(Nc4cc(OCC5CC5)c(N5CCNCC5)cn4)nc3c21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.25 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P36888 | FLT3 | Homo sapiens | Human | PF00047 PF07714 | 9.1 | IC50 | BindingDB |
| P10721 | KIT | Homo sapiens | Human | PF00047 PF07714 | 7.0 | IC50 | BindingDB |
| P11802 | CDK4 | Homo sapiens | Human | PF00069 | 6.5 | IC50 | BindingDB |
| Q00534 | CDK6 | Homo sapiens | Human | PF00069 | 6.4 | IC50 | BindingDB |