Molecule Details
InChIKeyYAEMHJKFIIIULI-UHFFFAOYSA-N
Compound NameAR-A014418
Canonical SMILESCOc1ccc(CNC(=O)Nc2ncc([N+](=O)[O-])s2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.13
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01950
Drug NameAR-AO-14418
CAS Number487021-52-3
Groups experimental
ATC Codes nan
Descriptionnan
Categories: Amides Glycogen Synthase Kinase 3, antagonists & inhibitors Sulfur Compounds
Cross-references: BindingDB: 50229962 CHEMBL259850 ChemSpider: 394949 PDB: TMU PubChem:448014 PubChem:46507570 ZINC: ZINC000003818778
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P49840 GSK3A Homo sapiens Human PF00069 7.3 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P49841 GSK3B Glycogen synthase kinase-3 beta inhibitor targets
P49840 GSK3A Glycogen synthase kinase-3 alpha other/unknown targets