Molecule Details
| InChIKey | XZJTXLBTECDTKJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(2-fluoro-4-sulfamoylphenyl)-4-oxochromene-3-carboxamide |
| Canonical SMILES | NS(=O)(=O)c1ccc(NC(=O)c2coc3ccccc3c2=O)c(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.25 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 8.2 | Ki | ChEMBL |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.5 | Ki | ChEMBL |
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 7.3 | Ki | ChEMBL |
| P22748 | CA4 | Homo sapiens | Human | PF00194 | 7.3 | Ki | ChEMBL |
| P27338 | MAOB | Homo sapiens | Human | PF01593 | 7.2 | IC50 | ChEMBL |
| Q9Y2D0 | CA5B | Homo sapiens | Human | PF00194 | 7.2 | Ki | ChEMBL |
| P35218 | CA5A | Homo sapiens | Human | PF00194 | 7.1 | Ki | ChEMBL |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 6.2 | Ki | ChEMBL |