Molecule Details
| InChIKey | XZIQSOZOLJJMFN-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(4-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide |
| Canonical SMILES | O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccncc1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.52 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P48995 | TRPC1 | Homo sapiens | Human | PF00520 PF08344 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q13507 | TRPC3 | Homo sapiens | Human | PF12796 PF00520 PF08344 | 6.5 | IC50 | ChEMBL |
| Q13586 | STIM1 | Homo sapiens | Human | PF25578 PF07647 PF16533 | 6.5 | IC50 | ChEMBL |
| Q96D31 | ORAI1 | Homo sapiens | Human | PF07856 | 6.5 | IC50 | ChEMBL |