Molecule Details
InChIKeyXYZNKCSDQRKAFR-UHFFFAOYSA-N
Compound Name4-amino-2-(3,4-dichlorophenyl)-N-(1H-indazol-5-yl)butanamide
Canonical SMILESNCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)53
Pfam Stratification Cross-Family
Avg pChEMBL6.94
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (53)
Target Gene Organism Category Pfam pChEMBL Type Source
P51817 PRKX Homo sapiens Human PF00069 9.0 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 8.9 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 8.7 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.4 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 8.4 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 8.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.3 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 8.0 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 8.0 Ki ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 7.7 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.7 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 7.7 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 7.7 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 7.6 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 7.4 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 7.3 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 7.3 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.0 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 7.0 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.0 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.9 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.9 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.9 Ki ChEMBL
O15530 PDPK1 Homo sapiens Human PF14593 PF00069 6.8 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.7 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.5 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.5 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.5 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.5 Ki ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q8TDC3 BRSK1 Homo sapiens Human PF21122 PF00069 PF21115 6.4 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P41743 PRKCI Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.3 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.3 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.2 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.2 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.0 Ki ChEMBL
Q05513 PRKCZ Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.0 Ki ChEMBL