Molecule Details
| InChIKey | XYWIPYBIIRTJMM-IBGZPJMESA-N |
|---|---|
| Canonical SMILES | CC[C@@H](C(=O)Nc1ccc(C(N)=O)c(F)c1)n1cc(OC)c(-c2cc(Cl)ccc2-n2cc(C(F)(F)F)nn2)cc1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.64 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19088 |
|---|---|
| Drug Name | Asundexian |
| CAS Number | 2064121-65-7 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Asundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke). |
Categories: Acids, Carbocyclic Amides Benzene Derivatives Benzoates Hydrocarbons, Halogenated
Cross-references: BindingDB: 413842 ChemSpider: 115009501 PDB: QV3 Wikipedia: Asundexian
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P03951 | F11 | Coagulation factor XI | inhibitor | targets |