Molecule Details
| InChIKey | XYDNMOZJKOGZLS-NSHDSACASA-N |
|---|---|
| Canonical SMILES | C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(-c3cnn(C)c3)nc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.51 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12048 |
|---|---|
| Drug Name | Savolitinib |
| CAS Number | 1313725-88-0 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others. |
Categories: Tyrosine Kinase Inhibitors
Cross-references: BindingDB: 50023342 CHEMBL3334567 ChemSpider: 34501055 PDB: V0L PubChem:68289010 PubChem:347828359 Wikipedia: Savolitinib ZINC: ZINC000149738712
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P08581 | MET | Hepatocyte growth factor receptor | inhibitor | targets |