Molecule Details
| InChIKey | XXQLCMDLJMBMLB-ZSEKCTLFSA-N |
|---|---|
| Compound Name | 5-[3-[4-(4-Chloro-2-methoxy-phenyl)-1-piperidyl]-2-methyl-3-oxo-propyl]-5-(methoxymethyl) imidazolidine-2,4-dione |
| Canonical SMILES | COC[C@]1(C[C@H](C)C(=O)N2CCC(c3ccc(Cl)cc3OC)CC2)NC(=O)NC1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.38 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UKP5 | ADAMTS6 | Homo sapiens | Human | PF17771 PF19236 PF05986 PF01562 PF08686 PF01421 PF19030 PF00090 | 7.9 | IC50 | BindingDB |
| P78536 | ADAM17 | Homo sapiens | Human | PF16698 PF00200 PF13574 | 7.1 | IC50 | ChEMBL;BindingDB |
| Q9UNA0 | ADAMTS5 | Homo sapiens | Human | PF17771 PF19236 PF05986 PF01421 PF19030 PF00090 | 7.1 | IC50 | ChEMBL;BindingDB |