Molecule Details
| InChIKey | XVUSHGLGCAFDEU-RTBURBONSA-N |
|---|---|
| Compound Name | US11203594, Example 28 |
| Canonical SMILES | COCCN1CC2(CC(n3c(=O)c(C(C)=O)c(C)c4cnc(N[C@@H]5CCOC[C@H]5O)nc43)C2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.72 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11802 | CDK4 | Homo sapiens | Human | PF00069 | 8.0 | Ki | ChEMBL;BindingDB |
| P24385 | CCND1 | Homo sapiens | Human | PF02984 PF00134 | 8.0 | Ki | ChEMBL |
| P30281 | CCND3 | Homo sapiens | Human | PF02984 PF00134 | 7.4 | Ki | ChEMBL |
| Q00534 | CDK6 | Homo sapiens | Human | PF00069 | 7.4 | Ki | ChEMBL;BindingDB |