Molecule Details
InChIKeyXVECMUKVOMUNLE-UHFFFAOYSA-N
Compound NameFR-180204
Canonical SMILESNc1n[nH]c2nnc(-c3c(-c4ccccc4)nn4ccccc34)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.51
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07794
Drug Name5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan
Cross-references: BindingDB: 50229978 ChEBI: 91383 CHEMBL259551 ChemSpider: 9668404 PDB: FRZ PubChem:11493598 PubChem:99444265 ZINC: ZINC000028565323
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P27361 MAPK3 Homo sapiens Human PF00069 6.5 Ki ChEMBL;BindingDB
P28482 MAPK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL;BindingDB
Q16539 MAPK14 Homo sapiens Human PF00069 6.5 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P28482 MAPK1 Mitogen-activated protein kinase 1 inhibitor targets