Molecule Details
InChIKeyXUKROCVZGZNGSI-CQSZACIVSA-N
Compound NameIrdabisant
Canonical SMILESC[C@@H]1CCCN1CCCOc1ccc(-c2ccc(=O)[nH]n2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.7
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12900
Drug NameIrdabisant
CAS Number1005402-19-6
Groups investigational
ATC Codes nan
DescriptionIrdabisant has been used in trials studying Cognitive Impairment.
Categories: Receptors, Histamine H3
Cross-references: BindingDB: 50350021 CHEMBL1829335 ChemSpider: 25991416 PubChem:25070031 PubChem:347829052 ZINC: ZINC000068250418
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P46098 HTR3A Homo sapiens Human PF02931 PF02932 8.7 Ki ChEMBL;BindingDB
Q9Y5N1 HRH3 Homo sapiens Human PF00001 8.7 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q9Y5N1 HRH3 Histamine H3 receptor antagonist targets