InChIKey	XTTZERNUQAFMOF-QMMMGPOBSA-N
Compound Name	Lorcaserin
Canonical SMILES	C[C@H]1CNCCc2ccc(Cl)cc21
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.19
Source	ChEMBL;BindingDB

DrugBank ID	DB04871
Drug Name	Lorcaserin
CAS Number	616202-92-7
Groups	approved withdrawn
ATC Codes	A08AA11
Description	Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorc...

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Categories: Alimentary Tract and Metabolism Antidepressive Agents Antiobesity Preparations, Excl. Diet Products Central Nervous System Depressants Centrally Acting Antiobesity Products Cytochrome P-450 CYP1A1 Substrates Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Heterocyclic Compounds, Fused-Ring Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 2c Receptor Agonists Serotonin 5-HT2 Receptor Agonists Serotonin 5-HT2C Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists

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Cross-references: BindingDB: 50161646 ChEBI: 65353 CHEMBL360328 ChemSpider: 9833595 D06613 PDB: T4U PubChem:11658860 PubChem:310264855 RxCUI: 1300701 Wikipedia: Lorcaserin ZINC: ZINC000006733300