Molecule Details
| InChIKey | XSOUHEXVEOQRKJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-fluoro-2,3,3a,9a-tetrahydro-1H-[1,4]benzodioxino[2,3-c]pyrrole |
| Canonical SMILES | Fc1cccc2c1OC1CNCC1O2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 14 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.7 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (14)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 8.9 | Ki | BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 8.8 | Ki | BindingDB |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 8.1 | Ki | BindingDB |
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 6.9 | Ki | BindingDB |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 6.8 | Ki | BindingDB |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 6.3 | Ki | BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P28221 | HTR1D | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P28222 | HTR1B | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P31645 | SLC6A4 | Homo sapiens | Human | PF03491 PF00209 | 6.0 | Ki | BindingDB |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |