Molecule Details
| InChIKey | XSNARVIBTBLTRJ-ZRKZCGFPSA-N |
|---|---|
| Compound Name | US20240132525, Example 029a |
| Canonical SMILES | Cc1cnc(Nc2cc(F)c3c(c2)COB3O)nc1NC1COCC[C@@H]1C#N |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.52 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P23458 | JAK1 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 10.7 | IC50 | BindingDB |
| O60674 | JAK2 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 8.4 | IC50 | BindingDB |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 6.4 | IC50 | BindingDB |