Molecule Details
InChIKeyXSHQBIXMLULFEV-UHFFFAOYSA-N
Compound Name1-Tert-butyl-3-naphthalen-1-ylpyrazolo(3,4-d)pyrimidin-4-amine
Canonical SMILESCC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.76
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P24941 CDK2 Homo sapiens Human PF00069 7.8 IC50 ChEMBL
Q02156 PRKCE Homo sapiens Human PF00130 PF00168 PF00069 PF00433 7.7 IC50 ChEMBL
Q9UQM7 CAMK2A Homo sapiens Human PF08332 PF00069 7.0 IC50 ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.0 IC50 ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 6.9 IC50 ChEMBL;BindingDB
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.9 IC50 ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
O14939 PLD2 Homo sapiens Human PF00614 PF13091 PF00787 6.5 IC50 BindingDB
P45983 MAPK8 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
Q13393 PLD1 Homo sapiens Human PF00169 PF00614 PF13091 PF00787 6.4 IC50 BindingDB
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.2 IC50 ChEMBL;BindingDB
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.2 IC50 ChEMBL;BindingDB
Q15139 PRKD1 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 IC50 ChEMBL;BindingDB