4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-pyrimidin-4-ylpyrimidin-2-amine

InChIKey	`XQLHPFMGKSLXAG-UHFFFAOYSA-N`
Compound Name	4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-pyrimidin-4-ylpyrimidin-2-amine
Canonical SMILES	`Fc1ccc(-c2nc(C3CCNCC3)sc2-c2ccnc(Nc3ccncn3)n2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.07
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	6.2	IC50	ChEMBL;BindingDB
W7JX98	PKG	Plasmodium falciparum (isolate NF54)	Pathogen	PF00027 PF00069	7.9	IC50	ChEMBL