N-[6-(2-aminoethyl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine

InChIKey	`XQFHODAQACCOEF-UHFFFAOYSA-N`
Compound Name	N-[6-(2-aminoethyl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine
Canonical SMILES	`Cc1cc(Nc2nc(CCN)cn3c(-c4cn[nH]c4)cnc23)sn1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.21
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	7.1	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	7.1	pIC50	TTD_MultiTarget