Molecule Details
InChIKeyXOVPCPRZRHQFBI-UHFFFAOYSA-N
Compound Name1-(4-Hydroxy-2-methyl-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihydro-quinoline-3-carboxylic acid amide
Canonical SMILESCc1cc(O)ccc1-n1cc(C(N)=O)c(=O)c2ccc(-c3ccncc3)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)15
Pfam Stratification Cross-Family
Avg pChEMBL6.45
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (15)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.8 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.0 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.7 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.6 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.4 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P07384 CAPN1 Homo sapiens Human PF01067 PF13833 PF00648 6.3 IC50 ChEMBL;BindingDB
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O75676 RPS6KA4 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q14289 PTK2B Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.0 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.0 Ki ChEMBL