N-(3-Ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine

InChIKey	`XOTGKYTUNDYTBS-UHFFFAOYSA-N`
Compound Name	N-(3-Ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine
Canonical SMILES	`C#Cc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.14
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.7	IC50	ChEMBL;BindingDB
O14976	GAK	Homo sapiens	Human	PF00069 PF10409	7.7	IC50	ChEMBL;BindingDB
P09467	FBP1	Homo sapiens	Human	PF00316 PF18913	6.0	IC50	ChEMBL;BindingDB