Molecule Details
InChIKeyXNULRSOGWPFPBL-REWPJTCUSA-N
Canonical SMILESN#Cc1ccc(N2N=C3c4ccc(C(=O)O)cc4CC[C@@H]3[C@@H]2C2CCCC2)cc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.21
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11814
Drug NamePF-03882845
CAS Number1023650-66-9
Groups investigational
ATC Codes nan
DescriptionPF-03882845 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 and Type 2 Diabetic Nephropathy.
Categories: Benzene Derivatives Heterocyclic Compounds, Fused-Ring Hydrocarbons, Chlorinated Hydrocarbons, Halogenated Pyrazoles
Cross-references: BindingDB: 50324210 CHEMBL1215331 ChemSpider: 25053860 PubChem:46871935 PubChem:347828161 ZINC: ZINC000058583489
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P08235 NR3C2 Homo sapiens Human PF00104 PF00105 8.0 IC50 ChEMBL;BindingDB
P06401 PGR Homo sapiens Human PF00104 PF02161 PF00105 6.4 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P08235 NR3C2 Mineralocorticoid receptor modulator targets