InChIKey	XNKLLVCARDGLGL-JGVFFNPUSA-N
Canonical SMILES	Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.22
Source	BindingDB;ChEMBL

DrugBank ID	DB00649
Drug Name	Stavudine
CAS Number	3056-17-5
Groups	approved investigational
ATC Codes	J05AR28 J05AF04 J05AR07
Description	A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

---

Categories: Agents Causing Muscle Toxicity Anti-HIV Agents Anti-Infective Agents Anti-Retroviral Agents Antiinfectives for Systemic Use Antimetabolites Antiviral Agents Antivirals for Systemic Use Antivirals used in combination for the treatment of HIV infections Deoxyribonucleosides Dideoxynucleosides Direct Acting Antivirals Enzyme Inhibitors Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor Neurotoxic agents Noxae Nucleic Acid Synthesis Inhibitors Nucleic Acids, Nucleotides, and Nucleosides Nucleoside Reverse Transcriptase Inhibitors Nucleoside and Nucleotide Reverse Transcriptase Inhibitors Nucleosides OAT1/SLC22A6 Substrates Pyrimidine Nucleosides Pyrimidines Reverse Transcriptase Inhibitors Toxic Actions

---

Cross-references: BindingDB: 50013111 ChEBI: 63581 CHEMBL991 ChemSpider: 17270 Drugs Product Database (DPD): 66 C07312 D00445 PharmGKB: PA451494 PubChem:18283 PubChem:46506943 RxCUI: 59763 Therapeutic Targets Database: DAP000172 Wikipedia: Stavudine ZINC: ZINC000000137884