Molecule Details
| InChIKey | XMYKNCNAZKMVQN-NYYWCZLTSA-N |
|---|---|
| Canonical SMILES | NC(=S)N/N=C/c1ncccc1N |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.57 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB11940 |
|---|---|
| Drug Name | Triapine |
| CAS Number | 143621-35-6 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others. |
Categories: Semicarbazides Semicarbazones Sulfur Compounds
Cross-references: BindingDB: 50198892 CHEMBL231616 ChemSpider: 7846300 PharmGKB: PA165858618 PubChem:9571836 PubChem:347828267 Wikipedia: 3-Aminopyridine-2-carboxaldehyde_thiosemicarbazone ZINC: ZINC000006092213
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P31350 | RRM2 | Ribonucleoside-diphosphate reductase subunit M2 | modulator | targets |