Molecule Details
InChIKeyXMDRTFUFPOAGDR-UHFFFAOYSA-N
Compound Name6-(1-azepanyl)-N,2-dicyclopropyl-5-methyl-4-pyrimidinamine
Canonical SMILESCc1c(NC2CC2)nc(C2CC2)nc1N1CCCCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.01
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P20309 CHRM3 Homo sapiens Human PF00001 8.5 Ki ChEMBL;BindingDB
P08173 CHRM4 Homo sapiens Human PF00001 8.0 Ki ChEMBL
P11229 CHRM1 Homo sapiens Human PF00001 7.7 Ki ChEMBL
P08912 CHRM5 Homo sapiens Human PF00001 7.2 Ki ChEMBL
P08172 CHRM2 Homo sapiens Human PF00001 7.1 Kd ChEMBL
P27815 PDE4A Homo sapiens Human PF18100 PF00233 6.2 IC50 ChEMBL
Q07343 PDE4B Homo sapiens Human PF18100 PF00233 6.2 IC50 ChEMBL
Q08493 PDE4C Homo sapiens Human PF18100 PF00233 6.2 IC50 ChEMBL
Q08499 PDE4D Homo sapiens Human PF18100 PF00233 6.2 IC50 ChEMBL