N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-ylthio)phenyl)cyclopropanecarboxamide

InChIKey	`XLXSRNTZHMLTMP-UHFFFAOYSA-N`
Compound Name	N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-ylthio)phenyl)cyclopropanecarboxamide
Canonical SMILES	`Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CC4)cc3)nc3ccccc23)n[nH]1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.54
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75716	STK16	Homo sapiens	Human	PF00069	9.0	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.3	Ki	ChEMBL;BindingDB
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.3	Ki	ChEMBL;BindingDB