(2S)-2-amino-4-(((2S,3S,4R,5R)-5-(4-amino-5-cyanopyrrolo(2,3-d)pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl)methylsulfanyl)butanoic acid

InChIKey	`XLTWYAYAFLGUEQ-OPYVMVOTSA-N`
Compound Name	(2S)-2-amino-4-(((2S,3S,4R,5R)-5-(4-amino-5-cyanopyrrolo(2,3-d)pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl)methylsulfanyl)butanoic acid
Canonical SMILES	`N#Cc1cn([C@@H]2O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]2O)c2ncnc(N)c12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.87
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q8TEK3	DOT1L	Homo sapiens	Human	PF08123	7.7	IC50	ChEMBL;BindingDB
P26358	DNMT1	Homo sapiens	Human	PF01426 PF06464 PF00145 PF12047 PF02008	6.8	IC50	ChEMBL;BindingDB
O60678	PRMT3	Homo sapiens	Human	PF21137 PF21336 PF06325 PF22528	6.1	IC50	ChEMBL;BindingDB