N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)benzamide

InChIKey	`XLFJEGWLJGWRSM-UHFFFAOYSA-N`
Compound Name	N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)benzamide
Canonical SMILES	`CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5[nH]ncc45)c3)cc2C(F)(F)F)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	7.23
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q16539	MAPK14	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	7.4	IC50	ChEMBL
O43318	MAP3K7	Homo sapiens	Human	PF07714	7.1	IC50	ChEMBL
Q9NYL2	MAP3K20	Homo sapiens	Human	PF07714 PF07647	6.9	IC50	ChEMBL