Molecule Details
InChIKeyXJLXINKUBYWONI-DQQFMEOOSA-N
Compound Name[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2S,3R,4S,5S)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Canonical SMILESNC(=O)c1ccc[n+]([C@H]2O[C@@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OP(=O)(O)O)[C@@H]3O)[C@H](O)[C@@H]2O)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.99
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P13922 Plasmodium falciparum (isolate K1 / Thailand) Pathogen PF00186 PF00303 8.1 Ki ChEMBL
B0BL08 dfrA17 Escherichia coli Pathogen PF00186 6.4 Kd BindingDB
P0ABQ4 folA Escherichia coli (strain K12) Pathogen PF00186 6.4 Kd ChEMBL