Molecule Details
InChIKeyXIOOJUQFJYPVLA-UHFFFAOYSA-N
Compound Name5-amino-6-cyano-7-(furan-2-yl)-2-(furan-2-ylmethylidene)-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-8-carboxamide
Canonical SMILESN#CC1=C(N)n2c(sc(=Cc3ccco3)c2=O)=C(C(N)=O)C1c1ccco1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)17
Pfam Stratification Cross-Family
Avg pChEMBL6.36
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.8 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q8IW41 MAPKAPK5 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
O00418 EEF2K Homo sapiens Human PF02816 6.4 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49137 MAPKAPK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.1 Ki ChEMBL
P53350 PLK1 Homo sapiens Human PF00069 PF00659 6.0 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.0 Ki ChEMBL