Molecule Details
| InChIKey | XGXYGEYUGTVZAR-GFCCVEGCSA-N |
|---|---|
| Compound Name | (3R)-5-chlorospiro[2,4-dihydro-1H-naphthalene-3,2'-5H-1,3-oxazole]-4'-amine |
| Canonical SMILES | NC1=N[C@]2(CCc3cccc(Cl)c3C2)OC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.72 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 9.6 | Ki | ChEMBL |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 9.5 | Ki | ChEMBL |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 9.5 | Ki | ChEMBL |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 8.4 | Ki | ChEMBL |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 7.7 | Ki | ChEMBL |
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 7.6 | Ki | ChEMBL |