Molecule Details
InChIKeyXGMWRIIMIJPGBH-UHFFFAOYSA-N
Compound Name3-[(5-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]phenol
Canonical SMILESOc1cccc(Nc2ncnc3scc(Cl)c23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.35
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.8 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.7 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.5 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.3 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.0 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL